Jayson went to the market. He bought 1 and 1 over 2 pounds of salami for $3.75 .

Let's assume that Jayson bought 1.5 pounds of salami for $3.75.

To find the cost per pound of salami, we divide the total cost by the number of pounds:
Cost per pound = $3.75 / 1.5 pounds = $2.50/pound. Answer: \boxed{2.50}.