Which Supreme Court case would have had the BIGGEST impact on enslaved people in the United States?

Responses
A Marbury v. Madison (1803)Marbury v. Madison (1803)
B Plessy v. Ferguson (1896)Plessy v. Ferguson (1896)
C McCulloch v. Maryland (1819)McCulloch v. Maryland (1819)
D Dred Scott v. Sandford (1857)

D Dred Scott v. Sandford (1857)