A mutation that causes abnormal cell division can result in
Clogged arteries
Cystic Fibrosis
Sickle cell anemia
Skin cancer
A mutation that causes abnormal cell division most directly leads to "Skin cancer."
Here's an explanation of how each option is related to mutations:
1. Clogged arteries: While a person's genetic makeup can influence their risk of developing clogged arteries (atherosclerosis), this condition is primarily caused by a buildup of plaque in the artery walls. Plaque consists of fat, cholesterol, calcium, and other substances found in the blood. Lifestyle factors, such as diet, exercise, and smoking, play significant roles in the development of clogged arteries, not mutations causing abnormal cell division.
2. Cystic Fibrosis: This is a hereditary disease caused by a mutation in the CFTR gene, which affects the protein that regulates the movement of ions (including chloride) across cell membranes. This mutation leads to the production of thick, sticky mucus that can clog the lungs and obstruct the pancreas. It is not a condition caused by abnormal cell division.
3. Sickle cell anemia: This is an inherited form of anemia—a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout the body. It is caused by a mutation in the HBB gene that leads to the production of hemoglobin S, which distorts the shape of red blood cells into a sickle shape. This change can lead to various complications, but it is not the result of abnormal cell division.
4. Skin cancer: Mutations that lead to abnormal cell division are most closely associated with cancer, including skin cancer. If the mutations occur in genes that control cell growth and division, they can cause cells to multiply uncontrollably, which is characteristic of cancer. In the case of skin cancer, this is often triggered by mutations induced by UV radiation from the sun or tanning beds, which affect skin cell DNA.