List 3 signs or indicators that a chemical reaction has occurred.

There are various signs that may indicate a chemical reaction has occurred. Here are three common indicators:

1. **Color Change**: A change in color can be a sign of a chemical reaction. For instance, when iron rusts, there is a color change from metallic gray to reddish-brown. This indicates that iron has reacted with oxygen to form iron oxide.

2. **Formation of a Precipitate**: If a solid substance forms from a solution where previously there were only dissolved substances, this is a sign of a chemical reaction. The solid that forms is known as a precipitate. An example is when solutions of silver nitrate and sodium chloride are mixed, a white precipitate of silver chloride forms.

3. **Gas Production**: The formation of gas bubbles in a liquid is often a sign of a chemical reaction taking place, particularly if the reaction system was previously a liquid or a solid. The production of gas might be visible as bubbling or fizzing in the reaction mixture. This happens, for example, when vinegar (acetic acid) reacts with baking soda (sodium bicarbonate), producing carbon dioxide gas.

Other signs that a chemical reaction has occurred may include temperature change (exothermic or endothermic reactions), odor change (production or loss of volatile substances), or the emission of light or sound. However, it's important to note that the presence of one or more of these indicators doesn't always guarantee that a chemical reaction has taken place as some physical changes can exhibit similar characteristics (e.g. sublimation can involve a change of state without a chemical reaction). Therefore, to confirm that a chemical reaction has occurred, these indicators are usually considered alongside other evidence, such as changes in chemical properties or the formation of new substances.