Long-term risk of smoking includes

several serious health conditions and diseases. Some of the long-term risks of smoking include:

1. Lung cancer: Smoking is the leading cause of lung cancer, and long-term smokers have a significantly higher risk of developing this deadly disease.

2. Chronic obstructive pulmonary disease (COPD): Smoking is the primary cause of COPD, which includes conditions such as chronic bronchitis and emphysema. These diseases gradually damage the airways and make breathing difficult.

3. Heart disease: Smoking damages blood vessels and increases the risk of heart disease, including heart attacks, strokes, and blocked arteries. It can also lead to high blood pressure and increased levels of bad cholesterol.

4. Respiratory infections: Smoking weakens the immune system and damages the respiratory system, making smokers more vulnerable to respiratory infections such as pneumonia and bronchitis.

5. Reduced fertility: Smoking can negatively impact both male and female fertility. In women, it can lead to decreased egg quality, hormonal imbalances, and an increased risk of miscarriage. In men, smoking can lower sperm count and motility.

6. Increased risk of other cancers: Smoking is linked to various types of cancer apart from lung cancer, including cancers of the mouth, throat, esophagus, pancreas, kidney, bladder, cervix, and stomach.

7. Premature aging: Smoking accelerates the aging process, causing premature wrinkles, sagging skin, and a dull complexion. It also damages the skin's elasticity and contributes to the formation of wrinkles around the mouth (known as smoker's lines).

8. Eye problems: Long-term smokers are at higher risk for eye problems such as cataracts, macular degeneration, dry eyes, and damage to the optic nerve, which can lead to vision loss.

9. Tooth and gum diseases: Smoking increases the risk of gum disease (periodontitis) and tooth decay. It can also cause teeth discoloration, bad breath, and a decreased sense of taste and smell.

10. Osteoporosis: Smoking weakens bones and increases the risk of developing osteoporosis, a condition characterized by brittle and fragile bones.

These long-term risks highlight the importance of quitting smoking and leading a smoke-free lifestyle to protect your health.