Question

"From here [Egypt] it spread to the entirety of the world, always moving along and advancing at set intervals. For it seemed to move as if by prearranged plan: it would linger for a set time in each place, just enough to make sure that no person could brush it off as a slight matter, and from there it would disperse in different directions as far as the ends of the inhabited world, almost as if it feared that any hidden corner of the earth might escape it.... This disease always spread out from the coasts and worked its way up into the interior.

- Procopius describing the Plague of Justinian that occurred from 541-542 C.E. (excerpt from the History of the Wars)

Using the prompt, which would be the most likely cause of the plague of Justinian?
Responses
A expansion of the Roman empire expansion of the Roman empire
B increased invasions by the Huns increased invasions by the Huns
C increased trade routes along the Silk Road increased trade routes along the Silk Road
D increased trade routes along the Mediterranean sea increased trade routes along the Mediterranean sea
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C increased trade routes along the Silk Road