If the usual adult dose of a drug is 120 mg, what would be the dose based on BSA for a person measuring 6 ft tall and weighing 200 lb.
To determine the dose based on Body Surface Area (BSA), we need to calculate the BSA using the Du Bois formula:
BSA (m²) = 0.007184 × height (cm)^0.725 × weight (kg)^0.425
First, we need to convert the height from feet to centimeters:
6 feet = 6 * 30.48 cm = 182.88 cm
Next, we need to convert the weight from pounds to kilograms:
200 lb = 200 * 0.4536 kg ≈ 90.72 kg
Now we can calculate the BSA:
BSA (m²) = 0.007184 × 182.88^0.725 × 90.72^0.425
BSA (m²) ≈ 2.03 m²
The dose based on BSA can be calculated by multiplying the BSA by the usual adult dose:
Dose based on BSA = BSA * usual adult dose
Dose based on BSA ≈ 2.03 m² * 120 mg
Dose based on BSA ≈ 243.60 mg
Therefore, the dose based on BSA for a person measuring 6 ft tall and weighing 200 lb would be approximately 243.60 mg.