Janina found that her playlist will play for 3.8×10^2 seconds, 6.3× 10^5 minutes, 1.05 × 10^4 hours, or 4.39814× 10^2 days. Which answer uses the most appropriate units?

The most appropriate units to use in this case are days, as they provide the largest value. Therefore, the answer that uses the most appropriate units is 4.39814 × 10^2 days.