1.What conditions can make systolic pressure to have the bigger difference with dystolic pressure?

2.Urine formation

1. There are several conditions that can cause an increased difference between systolic and diastolic blood pressure:

- Atherosclerosis: The buildup of plaque in the arteries can cause them to become stiff and narrow, resulting in higher systolic pressure and a larger difference between systolic and diastolic pressure.

- Hypertension: High blood pressure can cause the arteries to become narrower and less elastic, leading to an increased systolic pressure and a larger difference between systolic and diastolic pressure.

- Aging: As people age, the arteries naturally become stiffer and less flexible, which can result in a higher systolic pressure and a larger difference between systolic and diastolic pressure.

- Hyperthyroidism: Overactive thyroid function can cause an increase in heart rate and cardiac output, resulting in higher systolic pressure and a larger difference between systolic and diastolic pressure.

2. Urine formation is not directly related to the difference between systolic and diastolic blood pressure. Urine formation is a complex process that involves filtration, reabsorption, and secretion in the kidneys. It is influenced by factors such as fluid intake, blood pressure, and hormonal regulation. However, urinary function does not inherently affect the difference between systolic and diastolic blood pressure.