In what phase of mitosis do chromosomes split into sister chromatids? (1 point)

A. Prophase
B. Cytokinesis
C. Anaphase
D. Telophase

C. Anaphase

In the phase of mitosis where chromosomes split into sister chromatids is called C. Anaphase.

The phase of mitosis where chromosomes split into sister chromatids is called Anaphase. To determine the correct answer, we need to understand the different phases of mitosis and what happens in each phase.

Mitosis is the process by which a cell divides to create two identical daughter cells. It consists of several distinct phases, namely prophase, metaphase, anaphase, and telophase, followed by cytokinesis.

During prophase, the genetic material inside the cell condenses into visible structures called chromosomes. The nuclear membrane breaks down, and the spindle fibers start to form.

Metaphase is the phase where the chromosomes align at the center of the cell, forming a metaphase plate. The spindle fibers attach to the centromeres of the chromosomes.

In anaphase, the sister chromatids separate and move towards opposite poles of the cell. This movement is facilitated by the shortening of the spindle fibers. At this stage, each chromatid is considered a separate chromosome.

Finally, during telophase, the chromosomes reach the opposite poles of the cell. The spindle fibers disassemble, and the nuclear membrane reforms around each set of chromosomes.

Cytokinesis is the final step of cell division, which involves the separation of the cytoplasm and organelles into two daughter cells. This process is not directly related to the splitting of chromosomes.

Hence, the correct answer is C. Anaphase, as it is the phase in mitosis where the chromosomes split into sister chromatids.