True. One major reason why resting membrane potential is negative is because large, negatively charged proteins are trapped in the cell. These proteins, also known as intracellular proteins, cannot freely pass through the cell membrane due to their size and charge. As a result, they remain inside the cell, contributing to the overall negative charge within the cell. This negative charge contributes to the negative resting membrane potential of the cell.
True. One major reason why the resting membrane potential is negative is because large, negatively charged proteins are trapped inside the cell. These negatively charged proteins cannot easily pass through the cell membrane, creating an imbalance of charge across the membrane and contributing to the negative resting membrane potential.
