The Knights of Labor and the American Federation of Labor developed in response to the:

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Increased need to protect workers' interests.
Decreased power of political machines.
Increased demand for skilled workers.
Decreased profitability of the agricultural worker.
Other:

Other: concerns over working conditions, low wages, and the lack of worker rights and protections in the late 19th and early 20th centuries.

Increased need to protect workers' interests.

To determine the correct answer to this question, we need to understand the context and historical background of the Knights of Labor and the American Federation of Labor (AFL). Both organizations developed during the late 19th and early 20th centuries in the United States, when industrialization and urbanization were rapidly transforming the country.

The Knights of Labor was founded in 1869 as a secret society advocating for the rights and interests of all workers, regardless of their skills, gender, or race. It aimed to bring about significant social and economic reforms, including the eight-hour workday, equal pay for equal work, and the abolition of child labor. The organization gained widespread support among workers who were dissatisfied with the harsh working conditions and low wages prevalent during this time.

The American Federation of Labor, established in 1886, was a federation of trade unions representing skilled workers, such as carpenters, ironworkers, and electricians. Led by the influential labor leader Samuel Gompers, the AFL focused on specific demands, including better wages, improved working conditions, and the right to collective bargaining.

Based on this information, we can conclude that the correct answer to the question is: Increased need to protect workers' interests. Both the Knights of Labor and the American Federation of Labor developed in response to the growing concerns about the rights and well-being of workers during the period of industrialization and urbanization.