A cell contains DNA damage that causes it to undergo apoptosis before reaching mitosis. This cell had twice the amount of DNA for a cell of this type. During which checkpoint did this cell trigger apoptosis?(1 point) Responses
G1 Checkpoint
Checkpoint G2
Checkpoint M
No checkpoint meets these criteria.
No checkpoint meets these criteria.
In this scenario, the cell had twice the amount of DNA for a cell of this type, and it undergoes apoptosis before reaching mitosis. Given this information, we can deduce that the cell triggers apoptosis during the G2 checkpoint.
Therefore, the correct answer is: Checkpoint G2.
To determine during which checkpoint a cell triggers apoptosis in this scenario, we need to understand the checkpoints in the cell cycle and how they function.
The cell cycle consists of several checkpoints that regulate the progression of a cell through different phases of the cycle. These checkpoints are crucial for maintaining the integrity of the DNA and ensuring that cell division occurs properly.
The G1 checkpoint is the first major control point in the cell cycle. At this checkpoint, the cell checks for DNA damage and monitors the availability of essential nutrients and growth factors. If the DNA is damaged, the cell may undergo DNA repair, arrest its progress, or initiate apoptosis if the damage is irreparable.
The G2 checkpoint occurs after DNA replication during the S phase. At this checkpoint, the cell checks whether DNA replication has occurred correctly and whether the DNA is damaged or replicated incompletely. If DNA damage is detected, the cell can arrest progression and attempt DNA repair or initiate apoptosis.
The M checkpoint occurs during mitosis, which is the final phase of the cell cycle. At this checkpoint, the cell ensures that all chromosomes are correctly attached to the spindle fibers before separating. If chromosomes are not properly aligned, the cell can arrest progression until the error is corrected, or it may undergo apoptosis.
In this case, the cell has twice the amount of DNA for a cell of this type, indicating a DNA replication error. This suggests that the checkpoint that likely triggered apoptosis is the G2 checkpoint when the cell checked for DNA replication accuracy and potential DNA damage.
Therefore, the correct answer is: Checkpoint G2.