Which of the following is one way the Spanish impacted the Native Americans living in the southeastern region of North America?

Thousands of Native Americans abandoned their traditional beliefs and converted to Catholicism.
They formed a strong alliance and became trading partners.
The Native Americans were introduced to new foods.
Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

All of the given options show ways the Spanish impacted the Native Americans living in the southeastern region of North America. However, the option that specifically addresses the negative impact of diseases spread by contact with Europeans is: "Thousands of Native Americans died as a result of diseases spread by contact with Europeans."

One way the Spanish impacted the Native Americans living in the southeastern region of North America is that thousands of Native Americans abandoned their traditional beliefs and converted to Catholicism.

The way to determine which of the given options is true is to analyze each statement one by one and see if it aligns with the impact of the Spanish on Native Americans in the southeastern region of North America.

Option 1: Thousands of Native Americans abandoned their traditional beliefs and converted to Catholicism.
This statement is true. The Spanish brought Catholicism to the Americas and actively spread the religion. They established missions where Native Americans were taught Catholicism, leading to many Native Americans converting to the religion.

Option 2: They formed a strong alliance and became trading partners.
This statement is not entirely accurate. While there were cases of alliances and trading between some Native American groups and the Spanish, it was not a widespread phenomenon in the southeastern region. The Spanish were primarily interested in extracting resources rather than forming alliances.

Option 3: The Native Americans were introduced to new foods.
This statement is partly true. The Spanish did introduce new foods to the Native Americans, such as wheat, rice, and citrus fruits. However, the impact of this introduction was not as significant as the other options listed.

Option 4: Thousands of Native Americans died as a result of diseases spread by contact with Europeans.
This statement is true. The arrival of Europeans, including the Spanish, brought diseases to which Native Americans had no immunity. As a result, the Native American population in the southeastern region of North America was decimated by diseases like smallpox, measles, and influenza, leading to the deaths of thousands of Native Americans.

Therefore, the correct answer is: Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

a b c or d