During folliculogenesis in humans, oocytes become surrounded by somatic cells to from follicles. This occurs during fetal development in females. the somatic cells become granulosa cells, which act as nurse cells to provide supportive signals to the oocyte. Classically, the follicles progress through different stages of development; primordial follicles, primary follicles, secondary follicles, and antral follicles.

The stage of follicle development that corresponds to an oocyte surrounded by a single, squamous layer of granulosa cells would be the
blank1 - Word Answer

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follicle.
A/an
blank2 - Word Answer

follicle has an oocyte surrounded by a single layer of cuboidal granulosa cells.

blank1 - primary

blank2 - secondary

blank1: Primordial

blank2: Primary

The stage of follicle development that corresponds to an oocyte surrounded by a single, squamous layer of granulosa cells is the primordial follicle.

To understand this, let's break down the stages of follicle development:

1. Primordial Follicles: These are the earliest stage of follicle development. At this stage, the oocyte is surrounded by a single layer of squamous (flat) granulosa cells.

2. Primary Follicles: As folliculogenesis progresses, primordial follicles may develop into primary follicles. At this stage, the oocyte is still surrounded by a single layer of granulosa cells, but these cells are now cuboidal (cube-shaped).

3. Secondary Follicles: During this stage, the follicle continues to grow and the granulosa cells multiply to form multiple layers around the oocyte.

4. Antral Follicles: At this stage, the follicle has a fluid-filled cavity called an antrum, and the oocyte is still surrounded by multiple layers of granulosa cells.

Based on the provided information, we are looking for a follicle stage with a single layer of granulosa cells. This corresponds to the primordial follicle, where the oocyte is surrounded by a single layer of squamous granulosa cells. So, blank1 would be "primordial" and blank2 would be "primary."