We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable rights, that among these are life, liberty, and the pursuit of happiness. That, to secure these rights, governments are instituted among men, deriving their just powers from the consent of the governed. That, whenever any form of government becomes destructive of these ends, it is the right of the people to alter or to abolish it, and to institute new government, laying its foundation on such principles, and organizing its powers in such form, as to them shall seem most likely to effect their safety and happiness.

According to this excerpt, when do people have the right to overthrow a government
• when that government reorganizes and creates new institutions
when that government engages in destructive warfare
• when that government consents to give its power to the people
when that government takes away people's natural rights

• when that government becomes destructive of the rights mentioned (life, liberty, and the pursuit of happiness)

According to the excerpt, people have the right to overthrow a government when that government becomes destructive of the ends of securing the rights of life, liberty, and the pursuit of happiness.

According to the excerpt, people have the right to overthrow a government when that government becomes destructive of the rights mentioned, such as life, liberty, and the pursuit of happiness. Therefore, the correct answer is:

• when that government takes away people's natural rights.