12345-6789

The given sequence is a series of numbers: 12345-6789.

To subtract the number 6789 from 12345, follow these steps:

Step 1: Align the numbers vertically, putting the larger number (12345) on top and the smaller number (6789) below it.

```
12345
- 6789
```

Step 2: Start subtracting from the rightmost digit (ones place). Subtract 9 from 5: 5 - 9 = -4. Write down the -4 in the ones place.

```
12345
- 6789
-4
```

Step 3: Since 5 is smaller than 9, we need to borrow from the tens place. Change the 2 in the tens place to 1, and add the borrowed 10 to the ones place.

```
1
12345
- 6789
-4
```

Now, the ones place becomes 15 and the tens place becomes 1.

Step 4: Subtract the tens place digits: 4 - 8 (borrowed 1) = -4. Write down -4 in the tens place.

```
1
12345
- 6789
- 404
```

Step 5: Next, subtract the hundreds place digits: 4 - 7 (borrowed 1) = -3. Write down -3 in the hundreds place.

```
1
12345
- 6789
- 3404
```

Step 6: Finally, subtract the thousands place digits: 2 - 6 (borrowed 1) = -4. Write down -4 in the thousands place.

```
1
12345
- 6789
-43404
```

Thus, the difference of 12345 - 6789 is -43404.