Which statement is true regarding a chemical reaction

The total number of atoms
Even if the total
The total number of atoms changes
Even if the total number of atoms changes mass may not

The total number of atoms changes

The statement that is true regarding a chemical reaction is: "The total number of atoms changes." In a chemical reaction, atoms are rearranged and combined in different ways to form new substances. This means that the number and types of atoms involved in the reaction can change. However, it is important to note that while the total number of atoms may change, the total mass of the system will remain constant due to the law of conservation of mass.