Inhibition of the enzyme carbonic anhydrase would cause
A)an increase in blood volume
B)reduced water reabsorption in the collecting duct
C)a decrease in Ang production
D) an increase in GFR
E)a decrease in Na^ + reabsorption
B)reduced water reabsorption in the collecting duct
Inhibition of the enzyme carbonic anhydrase would cause:
E) a decrease in Na^+ reabsorption.
Carbonic anhydrase plays a crucial role in the reabsorption of sodium ions (Na^+) in the renal tubules. It catalyzes the conversion of carbon dioxide and water into carbonic acid, which further dissociates into bicarbonate ions (HCO3-) and hydrogen ions (H+). The bicarbonate ions are then reabsorbed into the bloodstream, along with sodium ions.
By inhibiting carbonic anhydrase, the conversion of carbon dioxide to bicarbonate ions is decreased. This leads to reduced reabsorption of bicarbonate ions and consequently decreases the reabsorption of sodium ions. As a result, there is a decrease in Na^+ reabsorption.