Stress induced release of ACTH from the pituitary gland is? has no affect on the immune sytem increases the immune response leads to fever causes release of cortisol from the adrenal gland which suppresses the immune system activates all the non-specific defense systems

causes release of cortisol from the adrenal gland which suppresses the immune system.

The stress-induced release of ACTH (adrenocorticotropic hormone) from the pituitary gland activates the production and release of cortisol from the adrenal gland, which in turn has various effects on the body. These effects include:

1. Suppression of the immune system: Cortisol can suppress the immune system by reducing the activity of immune cells, such as lymphocytes and macrophages. This suppression can impair the immune response to infections and make individuals more susceptible to illnesses.

2. Increase in the immune response: In response to stress, ACTH can also stimulate the release of certain molecules, such as cytokines, which are involved in immune response regulation. This can lead to an increase in immune response, particularly in the early stages of stress.

3. Activation of non-specific defense systems: Stress-induced release of cortisol can activate the body's non-specific defense systems, such as the innate immune response. This includes the release of inflammatory molecules and increased recruitment of immune cells to sites of injury or infection.

4. Fever: In some cases, stress-induced release of cortisol can lead to an increase in body temperature, resulting in fever. Fever is a response of the immune system aimed at enhancing immune activity and fighting off infections.

Overall, the stress-induced release of ACTH and subsequent cortisol production from the adrenal gland can have complex effects on the immune system, including suppression, activation, increased fever response, and activation of non-specific defense systems.