What would NOT happen due to a local increase in temperature?

• The Oxygen-Hemoglobin Saturation Curve would shift to the right.
• Oxygen would come off the hemoglobin.
• The affinity of hemoglobin for oxygen would increase.
Oxygen levels in the interstitial fluid would increase.
• The saturation of hemoglobin for oxygen would decline.

The affinity of hemoglobin for oxygen would increase.

The affinity of hemoglobin for oxygen would increase.