There are 6 bottles of water. Salt is added to the first one, a strong acid namely HCl to the 2nd one, a strong base namely calcium hydroxide to the 3rd one, a weak acid namely vinegar to the 4th one, a weak base namely baking soda to the 5th one and the 6th bottle of water is left in the same way.

Which bottle looks the least safe to drink from after leaving it for week?

The bottle with HCl added to it looks the least safe to drink from after leaving it for a week. HCl is a strong acid and can be harmful if ingested in large amounts.

Based on the substances added to each bottle, the least safe bottle to drink from after leaving it for a week would be the one with the strong acid, HCl, added to it.