Transformation gene therapy involves the direct alteration of a patient's genome through the delivery of exogenous genetic material into the cells, leading to permanent changes. On the other hand, transfection gene therapy involves the temporary introduction of genetic material into the cells, which only lasts for a limited time and does not affect the patient's genome.
Transformation and transfection are both types of gene therapies that aim to introduce new genetic material into target cells. However, the key difference between the two lies in the method of delivery. Transformation gene therapy involves the direct insertion of DNA into cells using techniques such as electroporation or viral vectors, while transfection gene therapy uses molecules like liposomes to deliver genetic material into cells. The choice between these approaches depends on the specific application and target cell type.
