5^2-81

= 25 - 81

= -56

To simplify the expression 5^2 - 81, we first need to calculate the value of 5^2 and then subtract 81.

Step 1: Calculate 5^2:
5^2 = 5 * 5 = 25

Step 2: Subtract 81 from 25:
25 - 81 = -56

Therefore, 5^2 - 81 = -56.