How did other countries respond when Portugal built a global empire?

They attacked Portuguese ships and trading posts.

They asked the pope to enforce the Treaty of Tordesillas.

They paid money to Portugal to keep the peace.

They formed an alliance and went to war against Portugal.

Some countries formed alliances and went to war against Portugal, while others paid tribute or negotiated treaties to maintain peace and access to trade. The pope did enforce the Treaty of Tordesillas, but some countries ignored it and established their own colonies in Portuguese territory.