(x + 4)2

This expression can be simplified using the FOIL method:

(x + 4)2 = (x + 4) * (x + 4)
= x * x + x * 4 + 4 * x + 4 * 4
= x^2 + 8x + 16

Therefore, (x + 4)2 simplifies to x^2 + 8x + 16.