A dna segment has base order AGC TTA TCG which copy exhibits a frameshift mutation through deletion
AGC TTT CG
CCA TAA CT
deletion
Chromosomes contain DNA.
epigenetic change
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To determine which copy of the DNA segment exhibits a frameshift mutation through deletion, we need to compare it with the normal or wild-type copy of the DNA segment. Let's refer to the wild-type DNA sequence as:
Wild-type DNA segment: AGC TTA TCG
A frameshift mutation occurs when nucleotides are inserted or deleted from the DNA sequence, resulting in a shift in the "reading frame." This alteration affects how the codons (three-letter sequences) are interpreted during protein synthesis.
In this case, you provided a DNA segment with the base order AGC TTA TCG. To determine if it has a frameshift mutation through deletion, we can compare it with the wild-type DNA segment.
Here is the comparison of the two sequences side by side:
Wild-type: AGC TTA TCG
Mutation: AGCTTATCG
As we can see, in the mutated sequence, there is an additional nucleotide "T" after the third base "C" compared to the wild-type sequence. This extra nucleotide causes a shift in the reading frame, resulting in a frameshift mutation.
Therefore, the copy of the DNA segment with the base order AGCTTATCG exhibits a frameshift mutation through deletion, where one nucleotide has been deleted, causing a shift in the reading frame.
BbyXBlue15
02/27/2021
Biology
High School
answered • expert verified
1. A DNA segment has base order AGC TTA TCG. Which copy exhibits a frameshift mutation through deletion?(1 point)
-AGC TCG
-AGC TTA TAG
-TTA TCG
-AGC TTT CG
2. A DNA segment has base order CCC ATA GCT. Which copy exhibits a deletion in the first codon triplet and then a substitution mutation?(1 point)
-CCA ATA GCT
-CCC TAG CT
-CCA YAA CT
-CCA TAG CT
3. Which type of mutation causes cystic fibrosis?(1 point)
-insertion
-deletion
-substitution
-silent
4. Which statement about chromosomes is true?(1 point)
-DNA contains chromosomes.
-The same number of chromosomes appears in haploid and body cells.
-Chromosomes contain DNA.
-Chromosomes are found in sets of three.
5. Which modification affects an organism’s expressed characteristics while leaving its DNA sequence unchanged?(1 point)
-insertion mutation
-substitution mutation
-deletion mutation
-epigenetic change
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A frameshift mutation involves the insertion or deletion of nucleotides in a DNA sequence, which modifies its open reading frame. A deletion is a mutation that involves the elimination of one nucleotide in DNA sequence.
With regard to the questions above described:
1. The sequence AGC TTT CG suffered a deletion of the Adenine (A) base at the second codon (i.e., AGC TTA TCG).
2. The sequence CCA TAG CT exhibits a deletion of the Cytosine (C) base at the first codon (i.e., CCC ATA GCT).
3. Cystic fibrosis is a recessive inherited disorder caused by a three-nucleotide (codon) deletion in the CF transmembrane conductance regulator (CFTR) gene. This deletion is associated with the loss of phenylalanine (Phe) amino acid in the exon 10 of the CFTR gene.
4. The statement 'chromosomes contain DNA' is TRUE. Chromosomes are thread-like structures that contain part or all of the genetic material (DNA) of an organism.
5. Epigenetic changes are modifications that affect an organism’s phenotype while leaving its DNA sequence. Epigenetic modifications include DNA methylation and histone modifications (e.g., histone acetylation, histone methylation).
In conclusion, frameshift mutations involve the modification of the Open Reading Frame. Deletion involves the elimination of a nucleotide in DNA. Chromosomes are thread-like structures that contain genetic material. Epigenetic modifications don't modify the genetic (nucleotide) sequence.