A scientist has noted a possible relationship between a certain chemical substance found in fish and the occurrence of kidney failure in humans. Which of the following preliminary steps should the scientist take before conducting a controlled experiment?
A. Establish a cause and effect relationship between the substance and the outcome.
B. Review the literature to determine what other research is available on this topic.
C. Write a research grant proposal to the appropriate federal funding agency.
D. Distribute letters of consent to human subjects who will be used in the research.

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  1. Review the literature to determine what other research is available on this topic.

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