1. I'd like you to meet my family.

2. This is my dad, mom and little brother.
3. This is my dad, my mom and my little brother.
4. This is my dad. This is my mom. And this is my little brother.
5. These are my dad, mom and little brother.
6. These are my dad, my mom and my little brother.
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From #2 to #6, which ones are grammatical? Can we use all the expressions

All are acceptable. I think we might use #5 or #6 when pointing to their photographs, the others when introducing them in person.

Others disagree, but I advise using the "Oxford comma". Your mom is not also your little brother. Use the comma before "and" in a series to make it clear.

Reed is correct. You should use the Oxford comma every time — that is, put in a comma before ‘and’ every time. Having it there avoids misinterpretation.

Here is an example of ambiguous wording when the Oxford comma was left out:

https://www.nytimes.com/2017/03/16/us/oxford-comma-lawsuit.html

Lots of money involved!!

In this case, all the expressions from #2 to #6 are grammatically correct and can be used interchangeably to introduce your family members. The difference lies in the style and emphasis of the sentences.

When introducing your family members, you have several options to convey the same meaning:

2. This is my dad, mom, and little brother.
- This expression is grammatically correct and commonly used.
- It uses a more concise form by omitting repeated possessive pronouns.

3. This is my dad, my mom, and my little brother.
- This expression is also grammatically correct and commonly used.
- It includes possessive pronouns before each family member, making it more explicit.

4. This is my dad. This is my mom. And this is my little brother.
- Each sentence in this expression is grammatically correct.
- It separates the introduction into three distinct sentences for added emphasis.
- This form is often used in a dramatic or suspenseful context.

5. These are my dad, mom, and little brother.
- This expression is grammatically correct and commonly used.
- It uses the plural form "are" to introduce multiple family members together.

6. These are my dad, my mom, and my little brother.
- This expression is also grammatically correct and commonly used.
- It includes possessive pronouns before each family member, making it more explicit.

So, you can use any of these expressions based on your personal preference and the context in which you are introducing your family members.