Chemistry

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what is the pH range of the buffering region?

is that when ph=pKa?

  • Chemistry -

    The best buffering is when pH = pKa. The RANGE, however, generally is considered to be +/- 1 from pKa. That's the definition of buffering capacity.

  • Chemistry -

    so if the pka is 4.5 the range will be from 3.5 to 5.5?

  • Chemistry -

    You can read more about it here.
    http://www.cartage.org.lb/en/themes/Sciences/Chemistry/Inorganicchemistry/AcidsBases/Acidsbasesindex/Bufferrange/Bufferrange.htm
    I think the buffer capacity is associated with the buffer range. The buffer capacity is defined as the amount of acid or base that can be added without exceeding +/- 1 in pH. The buffer range is the pH range that can be experience by the solution and still act as a buffer. And that is generally +/- 1 pH unit. Yes, in your case, that would be 3.5 to 5.5. A buffer with pKa 4.5 would be expected to work very well withing that range and would not be expected to work well outside that range.

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