Is this false??

When phosphate groups are joined together to make ATP, it gives off energy.

The statement "When phosphate groups are joined together to make ATP, it gives off energy" is actually true.

Now, let's break down how we can arrive at this answer:

1. Understanding ATP: Adenosine triphosphate (ATP) is a molecule that plays a crucial role in cellular energy storage and transfer. It consists of three phosphate groups attached to an adenosine molecule.

2. The Formation of ATP: ATP is formed through a process called phosphorylation, wherein a phosphate group is added to adenosine diphosphate (ADP) to form ATP. This process typically occurs through cellular respiration, specifically during the electron transport chain in aerobic respiration or substrate-level phosphorylation in anaerobic respiration.

3. Energy Release: The addition of a phosphate group to ADP to form ATP requires the input of energy, usually in the form of chemical energy derived from the breakdown of glucose or other fuels. This process is called an endergonic reaction or anabolic reaction.

4. Energy Release from ATP: When ATP is used as an energy source in cellular processes, it undergoes hydrolysis, where a phosphate group is removed by breaking the high-energy bond between the phosphate groups. This hydrolysis releases energy, which is used to power various cellular activities. This process is called an exergonic reaction or catabolic reaction.

Therefore, based on the explanation above, we can conclude that when phosphate groups are joined together to make ATP, it requires energy input, and when ATP is hydrolyzed to release energy, it gives off energy.