Biochemistry

What volumes of 25 mM CH3COOH and 25 mM NaCH3COO are required to prepare 300 mL of a 0.25 M buffer of pH = 5.0? (pKa = 4.76)

I keep getting something along the lines of 19ml for the conj. base..I know that's way wrong. help please!

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  1. Are you sure this problem is stated correctly? I don't see how we can mix 0.025M CH3COOH and 0.025M CH3COONa in any proportion and end up with a total of 0.25M. I might believe 0.025M but I don't see 0.25M.

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