Where in the human body is chromasome 17 located ( i mean like is it in the arm, leg, head). If possible, i would also like to know the comparison of normal and abnormal chroasome (when the abnormal is the alexander disease)
Well, if I remember correctly, the chromosomes are located in the nucleus of EACH cell.
Please only post your questions once. Repeating posts will not get a quicker response. In addition, it wastes our time looking over reposts that have already been answered in a later post. Thank you.
P.S., E.G. does remember correctly!
Chromosome 17 is found in the nucleus of almost all cells in the human body. It is one of the 23 pairs of chromosomes that contain our genetic material. Specifically, chromosome 17 is located in the cell nucleus and is not limited to any specific location in the body like the arm, leg, or head.
Now, let's discuss the comparison between a normal chromosome and an abnormal chromosome with respect to Alexander disease.
In normal cases, chromosome 17 consists of two copies, one inherited from each parent. It contains many genes that are essential for our biological functions, including the production of proteins that play important roles in various bodily processes.
In the case of Alexander disease, there is a specific genetic abnormality affecting chromosome 17. This disease is characterized by mutations in the gene known as GFAP (glial fibrillary acidic protein), which is located on chromosome 17. These mutations cause dysfunction and abnormal accumulation of the protein, leading to the destruction of certain cells in the brain called astrocytes.
Due to this abnormality on chromosome 17, individuals with Alexander disease may experience a range of symptoms such as developmental delays, movement abnormalities, intellectual disability, and changes in brain structure.
To identify the presence of this specific abnormality, medical professionals often use genetic testing methods, such as gene sequencing or DNA analysis, which can detect the mutations in the GFAP gene on chromosome 17.
It's important to note that not all abnormalities on chromosome 17 are associated with Alexander disease. Chromosome abnormalities can vary greatly in their effects on health and can be caused by various factors, including genetic mutations, rearrangements, or deletions. Each specific abnormality can have its own distinct impact on an individual's health and well-being.