Amniocentesis is most often recommended for women:

A. under 18 to detect defects and chromosomal Disorders
B. over age 35 to detect genetic defects and chromosomal disorders
C. who have Tay-Sachs disease to determine whether the baby has Down’s syndrome
D. who are between 8 and 13 weeks pregnant to determine whether the baby is developing normally

I choose B is that correct

I think so.

http://www.webmd.com/baby/guide/amniocentesis

i did some further reading and C can also be the correct answer.

Yes, you are correct. Amniocentesis is most often recommended for women who are over the age of 35 to detect genetic defects and chromosomal disorders.

Yes, choice B is correct. Amniocentesis is most often recommended for women over the age of 35 to detect genetic defects and chromosomal disorders. To arrive at this answer, you can break down each option:

A. Under 18 to detect defects and chromosomal disorders: This option is incorrect because amniocentesis is not typically recommended solely based on the mother's age alone.

B. Over age 35 to detect genetic defects and chromosomal disorders: This option is correct. Advanced maternal age (over 35) is considered a risk factor for genetic defects and chromosomal disorders such as Down syndrome, so amniocentesis is often recommended for women in this age group.

C. Who have Tay-Sachs disease to determine whether the baby has Down's syndrome: This option is incorrect. Amniocentesis is not specifically used for diagnosing Down syndrome in women with Tay-Sachs disease.

D. Who are between 8 and 13 weeks pregnant to determine whether the baby is developing normally: This option is incorrect. Amniocentesis is usually performed between 14 and 20 weeks of pregnancy, not during the first trimester.

Therefore, option B is the most appropriate answer.