Chemistry

posted by .

Assume that the normal blood buffer contains 0.00080 M carbonic acid and 0.0085 M hydrogen carbonate, the pKa = 6.35 for carbonic acid and the volume of blood in the body is 7.00 L. The blood pH, due to disruption is now 7.20. What is the ratio of [HCO3−]/[H2CO3] now that the blood has been challenged? How many moles of hydrogen carbonate must be added to the blood to bring the carbonic acid/hydrogen carbonate ratio back to a normal pH = 7.4? How many milliliters of 0.10 M hydrogen carbonate must be added to the blood?

  • Chemistry -

    First I would check to see what the pH is at these concentrations and I like to work in millimoles so
    base = 0.0085 x 7.00L = 59.5 mmols
    acid = 0.008 x 7.00L = 5.6 mmols.

    pH = 6.35 + log(59.5/5.6) = 7.38

    I look at the second part of the problem by asking how much acid must I add to the "normal" blood to make it pH of 7.20 and that will be how much bicarbonate I must add to get it back from 7.20 to normal 7.38.
    ........HCO3^- + H^+ ==> H2CO3
    I.......59.5..............5.6
    add..............x..............
    C.......-x......-x........+x
    E......59.5-x....0.......5.6+x

    Plug into the HH equation and solve for x, then add to 5.6 and subtract from 59.5

    I like to check to see that this actually produces the desired pH. Of course if this is how much acid must be added to produce that "off beat" pH of 7.20 it will be the bicarbonate that must be added to get it back to normal.

    You can find the ratio of the base/acid at pH 7.20 from the HH equation. Just plug in the values.

    E........................59.5+x

Respond to this Question

First Name
School Subject
Your Answer

Similar Questions

  1. chemistry

    how many moles of acid must be added to the blood to bring the carbonic acid/hydrogen carbonate ratio from 1:2 to 1:10?
  2. chemistry 2

    The volume of blood in the body of a certain deep-sea diver is 6.00L. Blood cells make up 55% of the blood volume, and the remaining 45% is the aqueous solution called plasma. What is the maximum volume of nitrogen measured at 1.00 …
  3. Chemistry-Please check

    When the kidneys secrete hydrogen ions, does the pH of the urine drop or is carbonic acid formed in the blood?
  4. chemistry

    Carbon Dioxide reacts with water in blood plasma to form carbonic acid. The equation for this reaction is showing on page 51. Suppose that you are a molecule of carbon dioxide. Describe the chemical reactions that take place when you …
  5. chemistry

    Carbon Dioxide reacts with water in blood plasma to form carbonic acid.Suppose that you are a molecule of carbon dioxide. Describe the chemical reactions that take place when you enter the blood and when you leave the blood. Explain …
  6. chemistry

    Carbon Dioxide reacts with water in blood plasma to form carbonic acid.Suppose that you are a molecule of carbon dioxide. Describe the chemical reactions that take place when you enter the blood and when you leave the blood. Explain …
  7. chemistry

    Carbon Dioxide reacts with water in blood plasma to form carbonic acid.Suppose that you are a molecule of carbon dioxide. Describe the chemical reactions that take place when you enter the blood and when you leave the blood. Explain …
  8. CHEMISTRY

    Carbon Dioxide reacts with water in blood plasma to form carbonic acid.Suppose that you are a molecule of carbon dioxide. Describe the chemical reactions that take place when you enter the blood and when you leave the blood. Explain …
  9. chemistry

    While you are at rest, your brain gets about 15% by volume of your blood. If your body contains 5.2 L of blood, how many liters of blood are in your brain at rest?
  10. Chemistry

    Our blood works mostly as a carbonic acid buffer which has an optimal buffering pH of about 6.4, the pH of blood is around 7.4. What is the advantage for the body of having the buffer at the non-optimal pH?

More Similar Questions