biochemical genetics

posted by .

After several rounds of experiments like those described above, you find that you have identified five different genes involved in the biosynthesis of tryptophan in this organism. You name them Gene 1 through Gene 5. Based on your knowledge of the pathway of tryptophan biosynthesis from Problem Set 2, you set out to compare this with the pathway in your new yeast species.

The figure below shows the pathway of tryptophan in most organisms.


You try growing a representative mutant from each complementation group (gene) on medium containing various intermediates in the tryptophan biosynthetic pathway and summarize your results in the table below. The symbol "+" indicates that a mutant in that gene grew when provided with only that compound in minimal medium. The symbol "-" indicates no growth under those conditions.

Compound Gene 1 Gene 2 Gene 3 Gene 4 Gene 5
Shikimate - - - - -
Shikimate-3-P - - - - -
Carboxyvinyl-3-P-shikimate - - - - -
Chorismate - - - - -
Anthranilate - - - + -
Phosphoribosyl anthranilate - - - + +
Carboxyphenylamino deoxyribulose-5P - + - + +
Indoleglycerol-P + + - + +
Indole + + - + +
Tryptophan + + + + +
Based on these data and the pathway shown above, give the most likely name of the enzyme encoded by each gene (when grading your answer, we will ignore capitalization, spaces, and dashes):

Gene 1
unanswered
Gene 2
unanswered
Gene 3
unanswered
Gene 4
unanswered
Gene 5

Respond to this Question

First Name
School Subject
Your Answer

Similar Questions

  1. SCIENCE

    HOW DO YOU REMEMBER WHICH GENES ARE WHICH! What do you mean which genes are which?
  2. genetics

    ______________ means that neither gene in a gene pair (genotype) masks the other. As a result, the traits carried by the 2 genes appear to be blended.
  3. Biology

    11. You are searching for a gene that traces its ancestry to an ancient gene in fish. Evolutionarily older fish, like the coelacanth, have only one copy of this gene. More modern fish, like a three-spine stickleback, have three. Modern …
  4. Statistics

    A study shows that the probability of a baby being born with gene x is 0.6. The probability of a baby being born with gene y is 0.7. (a)What is the probability of being born with both genes assuming that the probabilities are independent?
  5. Genetics

    1) For each of the following partial diploids, give the cellular phenotypes for A and B. Explain. A B a. for a negatively regulated gene: F’pR- poA-B/ pR po-AB- F’p-R p-oA-B/ pR- poAB- b. for a positively regulated gene: F’pR- …
  6. biochemical genetics

    You have discovered a new species of yeast and you would like to determine the pathway that this organism uses to synthesize the amino acid tryptophan. This yeast species can take up tryptophan, or synthesize it on its own if tryptophan …
  7. biology

    You have discovered a new species of yeast and you would like to determine the pathway that this organism uses to synthesize the amino acid tryptophan. This yeast species can take up tryptophan, or synthesize it on its own if tryptophan …
  8. intro to psychology

    Which one of the following statements about the Human Genome Project is not true?
  9. Genetics Help!!!!

    1 ) When the kinase ATM is activated after DNA damage occurs in the cell a. it can directly phosphorylate p53, which is then stabilized b. it can directly phosphorylate p53, which is then targeted for degradation by MDM2 c. it can …
  10. Biology Help Please!

    1) A transcriptional fusion of regulatory sequences of a particular gene with a reporter gene results in relatively uniform expression of the reporter gene in all cells of an organism, whereas a translational fusion with the same gene …

More Similar Questions