Statistics
posted by netspirit .
Prospective Cohort Study
The following tables show the crude and sexspecific results from a Prospective Cohort Study that examines the association between a binary exposure (E) and the development of a disease (D) during 20 years of followup.
Use these data to solve the above problem, it will become easier
Full data
D+ D Total
E+ 30 270 300
E 20 180 200
Total 50 450 500
Male
D+ D Total
E+ 12 108 120
E 8 72 80
Total 20 180 200
Female
D+ D Total
E+ 18 162 180
E 12 108 120
Total 30 270 300
1. Assume that this cohort is a simple random sample from a broader population of interest. Model the number of disease positive individuals among all exposed individuals in the sample using the binomial distribution with probability of disease ; and model the number of disease positive individuals among the unexposed in the sample using a binomial distribution, with probability of disease . Estimate , the proportion of exposed individuals who are disease positive, and provide an exact 95% confidence interval.
Estimated Proportion: ????
Confidence Interval:
Lower Bound:????
Upper Bound:????
and
4. Now, we examine the risk difference between the exposed and unexposed populations. Estimate the risk
difference for the disease and construct a corresponding largesample 95% confidence interval. Calculate the
risk difference as the proportion of diseased individuals in the exposed minus the proportion of diseased
individuals in the unexposed.
Risk Difference: ????
Confidence Interval:
Lower Bound: ????
Upper Bound: ????
Please help me count this two question, or explain.I need your help!

Cheating? For a free course where the certificate means nothing? LOL

You do realise that the questions are student specific? I've copied your table, for future reference.

Honour code...

Course does not study, its you who do it. Therefore course may be free or very expensive, but the gaining knowledge out of it is totally upto you.

please suggest the steps for solving this question. requesting you