Mendel did not know of the existence of chromosomes.Had he known, what change might he have made in his principle of independent assortment?

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he would not have taken true breed as he didnot know about crossing over.

To determine what change Gregor Mendel might have made to his principle of independent assortment if he had known about the existence of chromosomes, let's first understand the principle itself.

Mendel's principle of independent assortment states that the inheritance of one trait is independent of the inheritance of another trait. He observed this by conducting experiments with pea plants and analyzing the inheritance patterns of different traits, such as seed color and plant height.

As Mendel did not have knowledge of chromosomes, his experiments and conclusions were based solely on the visible physical characteristics of the traits he studied. However, had he known about chromosomes, he might have made adjustments to his principle.

Understanding chromosomes allows us to recognize that genes, which determine specific traits, are located on homologous pairs of chromosomes. The process of independent assortment during meiosis involves the random alignment and separation of these chromosome pairs.

Considering this, if Mendel had known about chromosomes, he might have modified his principle by explicitly specifying that the independent assortment of traits is influenced by the behavior of chromosomes during meiosis. He would likely have realized that the random alignment of chromosomes during gamete formation contributes to the independent assortment of genes and subsequent inheritance of traits.

In summary, if Mendel had known about the existence of chromosomes, he would have likely incorporated their behavior during meiosis into his principle of independent assortment, recognizing that the random alignment of homologous chromosome pairs influences the inheritance patterns of different traits.