What is the BEST way to determine taxomic relationship between 2 organisms

Since this is not my area of expertise, I searched Google under the key words "determine taxonomic relationship" to get these possible sources: (It helps if you spell the terms correctly.)

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Taxonomy.html
http://www.loa-cnr.it/Papers/dke2001.pdf
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TYX-445GF1R-4&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=4b73af3b2a1115b13e1dd539816e72bc
http://www.cs.vassar.edu/faculty/welty/papers/er2000/LADSEB05-2000.pdf
http://www.cs.toronto.edu/~jm/2507S/Readings/Welty.pdf

In the future, you can find the information you desire more quickly, if you use appropriate key words to do your own search.

I hope this helps. Thanks for asking.