what are the tenets of pharmacology

I found more then three "basic tenets of pharmacology" online:

The dose should be no larger than that necessary for the desired effect

The drug molecules must get so close to the cellular molecules that the function of the latter is altered

The drug molecules must be ‘bound’ to particular constituents of cells and tissues in order to produce an effect

Association of a drug molecule with its binding site leads to a physiological response

Most drug binds to protein molecules

To understand the tenets of pharmacology, it is important to know that pharmacology is the study of how drugs interact with the body. The tenets of pharmacology are the fundamental principles that guide the field. Here are five tenets of pharmacology:

1. Selectivity: Drugs should be selective in their action, targeting specific receptors, enzymes, or cellular components to produce the desired effect. This means that drugs should have minimal or no effects on other parts of the body to avoid unwanted side effects.

2. Potency and Efficacy: The dose of a drug should be no larger than necessary to achieve the desired therapeutic effect. The potency of a drug refers to its ability to produce the desired effect, while efficacy refers to the maximum effect a drug can produce. Finding the right balance between potency and efficacy is crucial for optimal drug therapy.

3. Pharmacokinetics: This refers to how drugs are absorbed, distributed, metabolized, and eliminated by the body. Understanding pharmacokinetics helps determine the appropriate dosage, administration route, and frequency of drug administration to achieve the desired therapeutic effect.

4. Pharmacodynamics: This involves studying how drugs interact with their target receptors or enzymes and how these interactions lead to physiological or therapeutic responses. Understanding the pharmacodynamics of a drug helps predict its effects and potential interactions with other drugs.

5. Safety: The safety of drugs is essential in pharmacology. Research and testing must be conducted to ensure that drugs are safe for use in humans, minimizing the risk of adverse reactions or harmful effects.

Remember, these tenets form the foundation of pharmacology, and there may be additional principles or variations depending on specific contexts or research areas within the field.