Expand and simplify the following: (x+8)(x-10)

To expand and simplify (x+8)(x-10), we use the distributive property:

(x+8)(x-10) = x*x + x*(-10) + 8*x + 8*(-10)
= x^2 - 10x + 8x - 80
= x^2 - 2x - 80

Therefore, (x+8)(x-10) simplifies to x^2 - 2x - 80.