A man possesses one copy of an allele for an autosomal dominant genetic condition. His wife does not possess the allele. What are the chances that their first daughter would inherit the condition?

If the man possesses one copy of an allele for an autosomal dominant genetic condition, he has a 50% chance of passing that allele on to his offspring. Since his wife does not possess the allele, their first daughter has a 0% chance of inheriting the condition. This is because the daughter would need to inherit the allele from both parents in order to express the condition.