How does anti phospholipid antibody of the mother cause iufd

Anti-phospholipid antibodies (APLAs) are antibodies that can mistakenly attack healthy cells and tissues in the body, including the placenta. When a pregnant woman has APLAs, these antibodies can interfere with the normal function of the placenta and disrupt the flow of blood and nutrients to the developing fetus.

This can lead to a condition known as placental insufficiency, where the placenta is unable to provide an adequate supply of oxygen and nutrients to the fetus. This can result in intrauterine fetal death (IUFD), where the fetus dies in the womb before birth.

In addition, APLAs can also increase the risk of blood clots forming in the placental blood vessels, further restricting blood flow to the fetus. This can lead to complications such as fetal growth restriction, preterm birth, or stillbirth.

Overall, the presence of anti-phospholipid antibodies in the mother can disrupt the normal development of the fetus and lead to IUFD. It is important for pregnant women with APLAs to receive appropriate monitoring and treatment to reduce the risk of adverse outcomes for both the mother and the baby.