Discuss stages of simple goiter.?

2. List the most important clinical signs of thyrotoxicosis.?
3. What is the most common presenting symptom of thyroid malignancies?

1. Stages of simple goiter:

- Stage 1: Initially, there may be no symptoms and the thyroid gland may enlarge slightly.
- Stage 2: As the goiter progresses, the thyroid gland may become visibly enlarged and may be felt as a lump in the neck.
- Stage 3: In some cases, the goiter may continue to grow and cause symptoms such as difficulty swallowing or breathing, hoarseness, and a feeling of pressure in the neck.

2. Clinical signs of thyrotoxicosis:

- Weight loss despite increased appetite
- Heat intolerance and increased sweating
- Tremors and nervousness
- Palpitations and fast heart rate
- Fatigue and muscle weakness
- Changes in menstrual patterns
- Diarrhea

3. The most common presenting symptom of thyroid malignancies is usually a painless lump or nodule in the thyroid gland. Other symptoms may include difficulty swallowing, hoarseness, or enlarged lymph nodes in the neck. In some cases, thyroid cancer may be asymptomatic and only detected through routine screening or imaging tests.