summarise in own words:

In the wake of the advent of genome editing technology CRISPR-Cas9 (clustered regularly interspaced palindromic repeat (CRISPR)-
associated protein 9), there has been a global debate around the implications of manipulating the human genome. While CRISPR-based germline gene editing is new, the debate about the ethics of gene editing is not – for several decades now, scholars have debated the ethics of making heritable changes to the human genome. The arguments that have been raised both for and against the use of genetic technologies in human reproduction reiterate much of the arguments made in the pre-CRISPR debate. As such, it is instructive for South Africa to reflect on these arguments now, in considering our position on the regulation of the use of this novel biotechnology. There are two dominant schools of thought in this area, bioliberalism and bioconservatism. Bioconservatives raise concerns about the risks of genetic manipulation, and argue that it ought to be limited or prohibited to avert these risks to human health and human nature. Bioliberal scholars are more open to the prospect of genetic manipulation, because of its potential utility. In this article, I conclude that in liberal democracies such as our own, bioliberal arguments ought to be seriously considered when formulating policy on human genome editing because of the extent to which they resonate with our Constitutional values and human rights. I further suggest that there is a need for an enquiry into the relevance of African perspectives on the ethical questions that arise concerning germline genome editing

The debate surrounding the ethics of manipulating the human genome using CRISPR-Cas9 technology has been ongoing for many years. Two main viewpoints, bioconservatism and bioliberalism, exist in this debate. Bioconservatives advocate for limitations or prohibition of genetic manipulation due to potential risks to human health and nature, while bioliberal scholars are more open to the idea for its potential benefits. In South Africa, it is important to consider these arguments when regulating the use of genome editing technology, as they align with Constitutional values and human rights. Additionally, there is a need to explore African perspectives on the ethical implications of germline genome editing.