Acute poisoning with acetaminophen often requires the use of a specific
antidote. The beneficial property of this antidote is that it
A. supplies sulfhydryl groups to detoxify a reactive metabolite
B. induces P450 enzymes to enhance elimination
C. blocks the metabolism of acetaminophen
D. enhances renal clearance of acetaminophen
E. chelates acetaminophen
A. supplies sulfhydryl groups to detoxify a reactive metabolite
The specific antidote for acetaminophen poisoning is N-acetylcysteine, which supplies sulfhydryl groups to detoxify the reactive metabolite produced during the metabolism of acetaminophen.