When you wake up and a large pimple greets you when you look into the mirror, this endocrine gland is to blame. Thymus gland, reproductive gland, thyroid gland, pancreas

The endocrine gland to blame for a large pimple is likely the sebaceous gland. The sebaceous glands are located in the skin and produce oil (sebum) that can contribute to the development of pimples when there is excess oil production or blockage of the pores.