What does pestilence mean as it is used in the following lines from Act V, Scene 2 of Romeo and Juliet?

Friar John: Going to find a barefoot brother out,
One of our order, to associate me,
Here in this city visiting the sick,
And finding him, the searchers of the town,
Suspecting that we both were in a house Where the infectious pestilence did reign,
Seal’d up the doors, and would not let us forth;
So that my speed to Mantua there was stay’d.
(1 point)
Responses

danger
danger

enemy
enemy

plague
plague

thoughts
thoughts

plague