risk factors for abdominal distension with splenomegaly

1. Chronic liver disease such as cirrhosis, which can lead to portal hypertension and splenomegaly.

2. Infections such as mononucleosis or malaria, which can cause swelling of the spleen.
3. Hematologic disorders such as leukemia or lymphoma, which can lead to enlargement of the spleen.
4. Inflammatory conditions such as autoimmune disorders or inflammatory bowel disease, which can also cause splenomegaly.
5. Certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or chemotherapy drugs, which can sometimes lead to enlargement of the spleen.
6. Congestive heart failure, which can cause fluid retention and lead to an enlarged spleen.
7. Parasitic infections such as schistosomiasis, which can lead to splenomegaly.
8. Genetic disorders such as sickle cell anemia or Gaucher's disease, which can also result in an enlarged spleen.