What happened to the region of the Byzantine Empire after it fell?(1 point)

Responses

It became an isolated region that many people abandoned.
It became an isolated region that many people abandoned.

It was divided into a collection of Greek city-states.
It was divided into a collection of Greek city-states.

It was conquered by the Holy Roman Empire.
It was conquered by the Holy Roman Empire.

It came under control of the Ottoman Empire.
It came under control of the Ottoman Empire.

It became an isolated region that many people abandoned.